4x21 When the Levee Breaks

Dean and Bobby lock Sam in Bobby’s panic room so he can detox from the demon blood, where Sam suffers from withdrawal symptoms, including hallucinations of being tortured by Alastair (Heyerdahl), berated by his teenage self (Ford), receiving support from his mother ([Πρέπει να είστε εγγεγραμμένοι και συνδεδεμένοι για να δείτε αυτόν το σύνδεσμο.]), and being rejected by Dean. As Bobby sees more seals are being broken, he tells Dean they should let Sam out to help them fight the impending Apocalypse. Dean disagrees and goes to Castiel for help. Castiel tells Dean that he must swear to serve God in order to save Sam, and Dean does so. However, Castiel goes behind the hunters' backs to secretly free Sam from the panic room for an unknown purpose. When Anna confronts him on it, Castiel turns her over to other angels to be taken to Heaven for punishment, still without explaining his motives for releasing Sam. Sam tries to dodge Dean and Bobby, and feeds on Ruby, who says that she has been missing because she has been working to uncover more information on Lilith. She reveals that few seals remain to be broken, and that only Lilith can break the last seal. Dean finally finds the couple; he tries to kill Ruby, and, when Sam defends her, has a blowout confrontation with Sam about the dark choices Sam has been making, calling him a monster. The two brawl violently, ending with Sam leaving with Ruby after Dean tells him to never come back.